River of Flame has clustered monsters and lava that only a Barbarian equipped with Leap or a Sorceress with Teleport can use the advantage of . In addition, Hephasto the Armor constantly wants to take down the players. If they manage to conquer these challenges and win, they'll be richly rewarded.
Chaos Sanctuary a.k.a. Diablo Run (Act 4)In the event that they don't get any significant or important items at the River of Flame, players can move on to next big area which is Diablo's stouthold itself, Chaos Sanctuary. In addition, it houses several of the most powerful and generous enemies of the game.
If the monsters do not drop any interesting items, then Diablo himself surely will. It's good to know that Diablo isn't too difficult to take down. Diablo's attacks are easy to avoid and even a budget Bonemancer build can take on him.
of the Damned. Act 4. Of The Damned (Act 4)The enemies of the City of the Damned are among the easiest of the entire late game destroy. They are relying on elemental and poison immunity , so it is possible that a Sorceress or Poison Nova Necromancer would want to stay clear of the area, but physical damage dealers cut through the crowds like butter.